Welcome to Biotranex!

Biotranex LLC is an innovative service company that offers a full range of drug metabolism, transport, pharmacokinetic, and analytic services to the biotech and pharmaceutical industries. Our extensive collective experience in the successful discovery and development of many marketed drugs allows us to apply innovative solutions to your ADMET needs. We take pride in helping our clients succeed.

 

ADME/PK service overview

Our services cover a broad spectrum of ADME, pharmacokinetic and toxicity studies. We tailor our capabilities to meet client’s needs.
Service list:



BILIRUBINcyte

  • Bilirubin glucuronide formation (UGT1A1) and transport (MRP2) inhibition assay for drug-induced hyperbilirubinemia
  • Accurate, robust, reproducible, and large dynamic range
  • Physiologically relevant hepatocyte suspension platform
  • Cross species comparison
  • In situ metabolism capability
  • Specific LC-MS/MS determination of bilirubin glucuronide
  • Cost-competitive
 

BSEPcyte

  • Bile salt export pump (BSEP, ABCB11) inhibition assay for DILI
  • Accurate, robust, reproducible, and large dynamic range
  • Physiologically relevant hepatocyte suspension platform
  • Cross species comparison
  • In situ metabolism capability
  • Specific LC-MS/MS determination of exported bile salts
  • Cost-competitive
  • Protected by US patent No. 9,772,325

MDR3cyte

  • Multidrug resistance protein 3 (MDR3, ABCB4) inhibition assay for DILI
  • Physiologically relevant hepatocyte suspension platform
  • Accurate, robust, reproducible, and large dynamic range
  • Cross species comparison
  • In situ metabolism of test drugs
  • Specific LC-MS/MS determination of exported phosphatidylcholine
  • Cost-competitive
  • Patent pending
 

Featured Services

webpic4.jpg

feed-image Feed Entries


COPYRIGHT © 2012 BIOTRANEX LLC.